Taking Effexor & Risperidone

Posted by Simon R. Downes on

I have been on Effexor for about 2 months to help with my social anxiety disorder. My doctor started me on 35.5mg a day for a week, then eventually upped to 75.5mg a day. At this point, I was feeling fine. Eventually, my doctor increased the dosage to 225mg and then 300mg. Oddly enough when the dosage increased, the effect was decreased. I am also taking Risperidone (2-4 tablets) before bedtime, could this be countering the effect of the Effexor?

Hello and thank you for your question about whether Risperidone is countering the effect of the Effexor.

Firstly, it is important to say that I am not a medical doctor (still in medical school), so I cannot comment on your medications. As I was trained as a psychologist, I first recommend non-pharmacological approaches to social anxiety disorder such as cognitive behavioral therapy.

Sometimes CBT plus a medication temporarily can be helpful. But ultimately, as the psychiatric drugs are so strong and unpredictable, I generally do not recommend them.

However, as I am now in medical school, and have experienced first-hand the positive effects of psychiatric medications with patients, I can admit their efficacy in certain severe cases.

If this is working for you, that is great. But I would like to ask you to become an expert on the medications you are taking. You can learn a great deal through certain web pages.

To learn more about the drugs you are taking and possible interactions through video, I recommend 'Doctor Mind' Dr. Mark Viner in Nevada. He is so honest about the drugs and you will learn a great deal that psychiatrists will not tell you.

Please watch the whole video.

He says it can be a good antidepressant, but watch what he says about taking too much....never above 225mg...(1:25)

it is mainly for depression - not good for anxiety: (6:20)
He says it can make you anxious...so that may explain the weaker anti-anxiety effect as the dosage becomes higher.

Here is another on Venlafaxine by him!

2. Please be aware that Risperidone can have very serious side effects:
Compare both drugs:

I do not know whether you have tried SSRIs, but they are often the first type of medication for symptoms of social anxiety (eg Paroxetine (Paxil) or Sertraline (Zoloft)). Risperidone, sold under the trade name Risperdal among others, is an antipsychotic medication. It is mainly used to treat schizophrenia, bipolar disorder, and irritability in people with autism.

If this doctor is not prescribing the right balance for you, I recommend that you try another. You will find the right balance. However please be careful about altering the dosage of Effexor suddenly - make sure you have a psychiatrist's guidance, for whatever changes you make. 

Lastly, if you are looking to reduce your anxiety speaking in front of others, or to boost your social confidence, I recommend Toastmasters; It worked wonders for me!
Thank you 


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